Creatine Supplementation Enhances Cognitive Performance During Sleep Deprivation

Sleep deprivation is a common challenge in our fast-paced world, often leading to decreased cognitive performance and impaired decision-making. Recent research published in Scientific Reports has highlighted the potential of creatine supplementation to mitigate these effects.​

In a controlled study, participants received a single high dose of creatine monohydrate (0.35 g/kg) during a period of sleep deprivation. The results were promising: participants exhibited improved cognitive performance and processing speed compared to those who received a placebo. Magnetic resonance spectroscopy revealed that creatine intake led to changes in cerebral high-energy phosphates, suggesting enhanced energy metabolism in the brain. Nature

🧬 Understanding Energy Metabolism and Sleep

The brain’s energy metabolism plays a crucial role in maintaining cognitive functions, especially during periods of sleep deprivation. Creatine serves as a buffer for adenosine triphosphate (ATP), the primary energy currency of cells, thereby supporting energy-demanding processes in neurons.​

However, individual responses to creatine supplementation can vary based on genetic factors influencing energy metabolism and sleep regulation. Understanding these genetic predispositions can help tailor effective strategies for managing sleep-related cognitive impairments.​Nature+7Nature+7Nature+7

🧬 Personalised Insights with CircleDNA

Gaining insights into your genetic makeup can provide a deeper understanding of how your body responds to factors like sleep deprivation and supplementation. The CircleDNA Premium Test Kit offers comprehensive analysis of genes related to sleep patterns, energy metabolism, and cognitive performance.​

By identifying your unique genetic traits, you can make informed decisions about lifestyle choices and interventions, such as creatine supplementation, to optimise your cognitive health.​

🧠 Conclusion: Enhancing Cognitive Resilience

The study underscores the potential of creatine supplementation as a strategy to enhance cognitive performance during sleep deprivation. Coupled with personalised genetic insights from the CircleDNA Premium Test Kit, individuals can develop tailored approaches to maintain cognitive resilience in challenging conditions.​Nature

📚 References (APA Style)

Gordji-Nejad, A., Matusch, A., Kleedörfer, S., Patel, H. J., Drzezga, A., Elmenhorst, D., Binkofski, F., & Bauer, A. (2024). Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation. Scientific Reports, 14, 4937. https://doi.org/10.1038/s41598-024-54249-9